In addition to picking the best niche for adsense, you also have options as to which ad type to show. The options are: 1) text & display 2) matched content 3) in-feed and 4) in-article.
In my own experiments, I’ve found higher click through rates with native in-article ads. Those ads perform the best on any of my sites.
The in-article ads will naturally blend with your content and display midway through your blog post. I like these types of ads because they are contextual and usually receive a good amount of clicks.
Sidebar ads are not as good since we are already trained to tune them out.
You can also try Matched Content if you have another content you’d like to promote